OXI στην Coca-cola Zero....(???)

    Sodium cyclamate is an artificial sweetener that was discovered in 1937 at the University of Illinois by graduate student Michael Sveda.

     Like many artificial sweeteners, the sweetness of cyclamate was discovered by accident. Michael Sveda was working in the lab on the synthesis of anti-fever medication. He put his cigarette down on the lab bench and when he put it back in his mouth he discovered the sweet taste of cyclamate.[...]

     Abbott intended to use cyclamate to mask the bitterness of certain drugs such as antibiotics and pentobarbital. In the US in 1958 it was designated GRAS (Generally Recognized as Safe).[...]

     Since 1969, its sale and use has been banned by the Food and Drug Administration in the United States.

     In 1966, a study reported that some intestinal bacteria could desulfonate cyclamate to produce cyclohexylamine, a compound suspected to have some chronic toxicity in animals. Further research resulted in a 1969 study which found the common 10:1 cyclamate:saccharin mixture to increase the incidence of bladder cancer in rats.[...]

     According to the Research Council committee cyclamate only increases the speed of cancer, accelerate the formation of tumours, and speed up tumour progression. In the nineteen-sixties cyclamate was banned from the United States because researchers found that "cyclamate/ saccharin mixtures” cause cancer.[..]

     Recently The Coca-Cola Company has began using it again for soft drinks such as Coca-Cola Zero or Nestea Light sold in countries where it isn't banned (large parts of South America, Asia, Africa and Europe).

Πηγή: http://en.wikipedia.org/wiki/Cyclamate